> The traditional Unix utilities to solve this problem are "lsof" and 
> "fuser". I don't know if OSX has either of these as standard, but they 
> are probably available as ports.

Or it might be "fstat", given that OSX is BSD-derived.
http://netbsd.gw.com/cgi-bin/man-cgi?fstat++NetBSD-4.0
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