Interesting timing ... there was just an article posted on Slashdot in
review of a new Bioinformatics book. 
http://books.slashdot.org/article.pl?sid=05/04/05/186212.  If nothing
else, it seems there is a lot of comments by bioinformatacists ... you
won't see any language specific discussions that would answer your
question, but you might find it interesting none-the-less.

Matt